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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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Études sur les capacités et la stabilité des antioxydants de l'acide 3-O-éthyl ascorbique, un inhibiteur cosmétique de la tyrosinase.

L'acide 3-O-éthyl ascorbique peut constituer un bon ingrédient blanchissant pour les cosmétiques. Cependant, avant de pouvoir être utilisé avec succès en cosmétique, sa biofonctionnalité et sa stabilité doivent être examinées de manière exhaustive. La réduction et la capacité de piégeage des radicaux libres du 2,2-diphényl-1-picrylhydrazyle (DPPH) de ce composé ont été analysées pour évaluer son potentiel antioxydant. De plus, la capacité d'inhibition de la tyrosinase a été analysée pour montrer la capacité de blanchiment de l'acide 3-O-éthyl ascorbique. La méthodologie de surface de réponse (RSM) a été utilisée pour déterminer les conditions optimales pour le dérivé d’acide ascorbique en cosmétique. D'après les résultats de la capacité de piégeage des radicaux du DPPH, la valeur de la concentration de demi-inhibiteur (CI50) de l'acide 3-O-éthyl ascorbique était de 0,032 g / L. Il a également montré une bonne capacité réductrice à une concentration de 1,5 g / L. Sur la base de l'analyse d'inhibition de la tyrosinase, la valeur de la CI50 était de 7,5 g / L. Les conditions optimales pour atteindre la meilleure stabilité ont été déterminées à partir du RSM à 36,3 ° C et à un pH de 5,46.


Source: https://www.ncbi.nlm.nih.gov/pubmed/30311899


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