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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/index.php
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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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Function: __construct

File: /home/orthodiedw/nutridatabase/index.php
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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/index.php
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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/index.php
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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/index.php
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Function: __construct

File: /home/orthodiedw/nutridatabase/index.php
Line: 315
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La preuve que l’effet radioprotecteur de l’acide ascorbique dépend du débit de dose de rayonnement.

De nombreuses études ont révélé que l'acide ascorbique (Aa) agit comme un puissant inhibiteur des dommages génétiques. L’objectif de la présente étude était d’évaluer l’effet radioprotecteur de Aa à deux débits de dose de rayonnement différents. Le test de mutation somatique et de recombinaison chez Drosophila melanogaster a été utilisé. Les larves de 48 h ont été traitées pendant 24 h avec 25, 50 et 100 mM de Aa. Après le prétraitement, les larves ont été irradiées avec 20 Gy de rayons gamma administrés à 36 ou 960 Gy / h. La toxicité, le taux de développement et la fréquence des taches mutantes ont été enregistrés. Les résultats fournissent la preuve d'un effet radioprotecteur pour toutes les concentrations testées de Aa uniquement lorsque 20 Gy ont été délivrés à 36 Gy / h et uniquement à 25 mM avec 960 Gy / h. Pour envisager l'utilisation de l'Aa comme radioprotecteur ou agent thérapeutique, il est nécessaire de connaître son potentiel dans différentes situations pour éviter les blessures non désirées.


Source: https://www.ncbi.nlm.nih.gov/pubmed/30081379


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