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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/index.php
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Line Number: 292

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/index.php
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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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Function: __construct

File: /home/orthodiedw/nutridatabase/index.php
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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/index.php
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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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Filename: drivers/Session_files_driver.php

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File: /home/orthodiedw/nutridatabase/application/controllers/Articles.php
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File: /home/orthodiedw/nutridatabase/index.php
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File: /home/orthodiedw/nutridatabase/index.php
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Modèles de décès chez les patients atteints de sepsie et utilisation d'hydrocortisone, d'acide ascorbique et de thiamine pour prévenir ces décès.

CONTEXTE: En général, les patients atteints de septicémie décèdent de la réponse de l'hôte à l'agent pathogène infectant plutôt que de l'agent pathogène infectant lui-même. Sept types de décès ont été identifiés dans la septicémie: choc vasoplégique, insuffisance respiratoire à un organe (syndrome de détresse respiratoire aiguë), insuffisance organique multisystémique (MSOF), et MSOF persistant avec inflammation persistante et immunosuppression avec infections récurrentes ( syndrome d’inflammation-immunosuppression persistante et catabolisme [PICS]). Pour améliorer les résultats des infections associées à la sepsie, des thérapies qui modulent le système immunitaire ont été testées; ces thérapies qui ont ciblé des molécules ou des voies spécifiques ont échoué universellement. CONCLUSION: Nous proposons que l'association de l'hydrocortisone, de l'acide ascorbique par voie intraveineuse et de la thiamine (traitement par THA), qui cible de manière synergique plusieurs voies, restaure le système immunitaire dérégulé et les lésions organiques, et réduit le risque de décès et de défaillance d'organe après une sepsie.


Source: https://www.ncbi.nlm.nih.gov/pubmed/30040533


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